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Technologies Offered:

Light Microscopy

  • Confocal microscopy (scanning and spinning-disk)
  • Two-photon microscopy
  • Wide-field fluorescence microscopy
  • Digital deconvolution
  • Transmitted-light imaging (phase, DIC, histology)
  • High-content screening (Confocal and Wide-field)
  • Super-resolution imaging (STORM, STED, SIM and AiryScan)
  • Cell surface imaging with <100 nM z-resolution (TIRF)
  • Specialized microscopy (FRAP, FRET, FCS, FLIP...)
  • Fluorescence lifetime imaging microscopy (FLIM)
  • Image Analysis expertise
  • Software for image analysis, processing, and deconvolution
    • Imaris, Volocity, SVI Huygens, SoftWoRx. Microvolution

Multiplexed Tissue Imaging

  • CODEX
  • Array Tomography

Atomic Force Microscopy

  • Bruker BioScope Resolve

Electron Microscopy

Transmission Electron Microscopy (biological)

  • Chemical and cryo-fixation/freeze substitution processing
  • High-Pressure Freezing (w/ opto and electric stimulation)
  • Immuno-EM
  • Correlative LM to EM: CELM
  • Negative staining
  • Ultramicrotomy, cryo and plastic
  • Electron tomography (plastic sections)

Scanning Electron Microscopy

  • Variable pressure/environmental
  • High resolution FE-SEM
  • Immuno-SEM
  • Array tomography SEM, CLEM

The Cell Sciences Imaging Facility (CSIF) is a Beckman Center supported university service center that provides high resolution, state-of-the-art light and electron microscopy technologies for imaging and analyzing the molecular and structural organization of cells, tissue and bioengineered materials.  The CSIF operates two sites at Stanford University: The SOM Beckman Center CSIF and the SOE Shriram Center CSIF.  Both facility sites are open to all members of the Stanford community as well as to external academic and industry researchers (with approval of the facility Director).

 

Events

March 26, 2019 to April 04, 2019

REGISTRATION*: https://www.leica-microsystems.com/stanford-tour/

Time & Date:
Seminar:
Tuesday, March 26th, @12pm
Hands-on:
March 26th to April 4th.
 
Location:
Seminar:
Beckman Center B100
Hands-on:
Beckman Center B456
By appointment.
 
Description:

Leica Microsystems is proud to announce the release of a new class of instruments—THUNDER Imaging Systems. They use Computational Clearing, a disruptive new method developed by Leica, to remove out-of-focus blur, and produce brilliant, haze-free images on a widefield microscope. You can learn more about this technology here.

To introduce THUNDER Imagers to the Stanford research community, Leica will be hosting a Workshop on March 26 – April 4. The workshop will open with a Lunch and Learn Seminar, and will be followed by hands-on demonstrations on the THUNDER Model Organism Imager and THUNDER 3D Tissue Imager. More information can be found below. Please contact Olga Davydenko (olga.davydenko@leica-microsystems.com) with any questions.